We are happy to announce that our paper “How Can Artificial Intelligence and Brain Connectivity Inform Outcome Prediction in Drug-Resistant Epilepsy?” has been published on IEEE Transactions on Artificial Intelligence. If you’re curious about how brain connectivity and AI can make epilepsy care more personalized, this scoping review summarizes 41 studies using structural/functional/effective connectomes to predict drug resistance, localize the epileptogenic zone, and forecast postsurgical and VNS outcomes. Overall, better results are consistently linked to resecting highly connected/aberrant network hubs overlapping the EZ, and AI models often improve prediction beyond traditional biomarkers—while highlighting current limits in sample size, heterogeneity, and explainability.